Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study
Identifieur interne : 000859 ( Main/Exploration ); précédent : 000858; suivant : 000860Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study
Auteurs : Honglei Chen ; Thomas H. Mosley ; Alvaro Alonso ; Xuemei HuangSource :
- American Journal of Epidemiology [ 0002-9262 ] ; 2009-03-18.
Abstract
Higher plasma urate concentration has been linked to lower risk of Parkinson's disease in men, but data are lacking on women and African Americans. The authors examined plasma urate in relation to Parkinson's disease in the biracial, population-based Atherosclerosis Risk in Communities (ARIC) cohort. Between 1987 and 1989, 15,792 participants, aged 4564 years, were recruited from 4 US communities and have since been followed with 3 triennial visits and annual surveillance. Plasma urate was measured at visits 1 and 2, and the concentrations were highly correlated. From visit 1 through 2004, 95 potential cases of Parkinson's disease were identified from multiple sources. Odds ratios and 95% confidence intervals were calculated from multivariate logistic regression models. Plasma urate concentration was inversely associated with Parkinson's disease occurrence. The odds ratios between extreme quartiles of plasma urate were 0.4 (95% confidence interval: 0.2, 0.8) in the overall analysis, 0.3 (95% confidence interval: 0.1, 0.7) for men, and 0.4 (95% confidence interval: 0.2, 1.0) for Caucasians. Such an association was also suggested among women and African Americans but was not statistically significant because of small sample sizes. These data support the previous finding that urate may be a protective factor against Parkinson's disease.
Url:
DOI: 10.1093/aje/kwp033
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study</title>
<author><name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
</author>
<author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H." last="Mosley">Thomas H. Mosley</name>
</author>
<author><name sortKey="Alonso, Alvaro" sort="Alonso, Alvaro" uniqKey="Alonso A" first="Alvaro" last="Alonso">Alvaro Alonso</name>
</author>
<author><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:6282A96CAAF2ADDA951D9515C54AC37C91F05F32</idno>
<date when="2009" year="2009">2009</date>
<idno type="doi">10.1093/aje/kwp033</idno>
<idno type="url">https://api.istex.fr/document/6282A96CAAF2ADDA951D9515C54AC37C91F05F32/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">000660</idno>
<idno type="wicri:Area/Main/Curation">000576</idno>
<idno type="wicri:Area/Main/Exploration">000859</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study</title>
<author><name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
<affiliation><wicri:noCountry code="no comma">E-mail: chenh2@niehs.nih.gov</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H." last="Mosley">Thomas H. Mosley</name>
</author>
<author><name sortKey="Alonso, Alvaro" sort="Alonso, Alvaro" uniqKey="Alonso A" first="Alvaro" last="Alonso">Alvaro Alonso</name>
</author>
<author><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">American Journal of Epidemiology</title>
<idno type="ISSN">0002-9262</idno>
<idno type="eISSN">1476-6256</idno>
<imprint><publisher>Oxford University Press</publisher>
<date type="published" when="2009-03-18">2009-03-18</date>
<biblScope unit="volume">169</biblScope>
<biblScope unit="issue">9</biblScope>
<biblScope unit="page" from="1064">1064</biblScope>
<biblScope unit="page" to="1069">1069</biblScope>
</imprint>
<idno type="ISSN">0002-9262</idno>
</series>
<idno type="istex">6282A96CAAF2ADDA951D9515C54AC37C91F05F32</idno>
<idno type="DOI">10.1093/aje/kwp033</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0002-9262</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract">Higher plasma urate concentration has been linked to lower risk of Parkinson's disease in men, but data are lacking on women and African Americans. The authors examined plasma urate in relation to Parkinson's disease in the biracial, population-based Atherosclerosis Risk in Communities (ARIC) cohort. Between 1987 and 1989, 15,792 participants, aged 4564 years, were recruited from 4 US communities and have since been followed with 3 triennial visits and annual surveillance. Plasma urate was measured at visits 1 and 2, and the concentrations were highly correlated. From visit 1 through 2004, 95 potential cases of Parkinson's disease were identified from multiple sources. Odds ratios and 95% confidence intervals were calculated from multivariate logistic regression models. Plasma urate concentration was inversely associated with Parkinson's disease occurrence. The odds ratios between extreme quartiles of plasma urate were 0.4 (95% confidence interval: 0.2, 0.8) in the overall analysis, 0.3 (95% confidence interval: 0.1, 0.7) for men, and 0.4 (95% confidence interval: 0.2, 1.0) for Caucasians. Such an association was also suggested among women and African Americans but was not statistically significant because of small sample sizes. These data support the previous finding that urate may be a protective factor against Parkinson's disease.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Alonso, Alvaro" sort="Alonso, Alvaro" uniqKey="Alonso A" first="Alvaro" last="Alonso">Alvaro Alonso</name>
<name sortKey="Chen, Honglei" sort="Chen, Honglei" uniqKey="Chen H" first="Honglei" last="Chen">Honglei Chen</name>
<name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name>
<name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H." last="Mosley">Thomas H. Mosley</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000859 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000859 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:6282A96CAAF2ADDA951D9515C54AC37C91F05F32 |texte= Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study }}
This area was generated with Dilib version V0.6.23. |